Mesonephric-like adenocarcinomas of the uterine corpus: report of a case series and review of the literature indicating poor prognosis for this subtype of endometrial adenocarcinoma.
Lars-Christian HornAnne Kathrin HöhnIrene KrückenMathias StillerUlrike ObeckChristine E BrambsPublished in: Journal of cancer research and clinical oncology (2020)
Uterine ML-AC represents a distinct subtype of invasive endometrial AC, associated with KRAS-mutations and characteristic immunohistochemical findings. Clinically, ML-AC may show an aggressive behavior with a high rate of recurrent disease and a substantial risk for distant metastatic disease, especially to the lungs.