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Mesonephric-like adenocarcinomas of the uterine corpus: report of a case series and review of the literature indicating poor prognosis for this subtype of endometrial adenocarcinoma.

Lars-Christian HornAnne Kathrin HöhnIrene KrückenMathias StillerUlrike ObeckChristine E Brambs
Published in: Journal of cancer research and clinical oncology (2020)
Uterine ML-AC represents a distinct subtype of invasive endometrial AC, associated with KRAS-mutations and characteristic immunohistochemical findings. Clinically, ML-AC may show an aggressive behavior with a high rate of recurrent disease and a substantial risk for distant metastatic disease, especially to the lungs.
Keyphrases
  • poor prognosis
  • long non coding rna
  • squamous cell carcinoma
  • small cell lung cancer
  • endometrial cancer
  • lymph node
  • locally advanced
  • rectal cancer