Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APP SAA knock-in mouse model of Alzheimer's disease.

Andrés NorambuenaVijay Kumar SagarZhuoying WangPrakash RautZiang FengHorst WallrabeEvelyn PardoTaylor KimShagufta Rehman AlamSong HuAmmasi PeriasamyGeorge S Bloom

Published in: bioRxiv : the preprint server for biology (2024)

mice, and may represent an early stage in human AD.

Keyphrases

early stage
mouse model
endothelial cells
functional connectivity
oxidative stress
resting state
induced pluripotent stem cells
high fat diet induced
heavy metals
pluripotent stem cells
squamous cell carcinoma
risk assessment
insulin resistance
wild type
rectal cancer