Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial.

Georgina M RussellKonstantinos KalafatakisClaire DurantNicola MarchantJamini ThakrarRussell ThirardJade KingJane BowlesThomas UptonNgoc Jade ThaiJonathan C W BrooksAileen WilsonKirsty PhillipsStuart FergusonMeryem GrabskiChris A RogersTheodoros LamprosSue WilsonCatherine HarmerMarcus MunafoStafford L Lightman

Published in: Journal of internal medicine (2023)

These findings support the administration of hormone therapy that mimics physiology.

Keyphrases

study protocol
phase iii
clinical trial
phase ii
sleep quality
randomized controlled trial
cerebral ischemia
mesenchymal stem cells
cell therapy
brain injury
double blind