First-trimester screening for trisomies in pregnancies with vanishing twin.

P ChaveevaA WrightArgyro SyngelakiL KonstantinidouD WrightK H Nicolaides

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2020)

First-trimester screening for trisomy in pregnancies with a vanishing twin should rely on a combination of maternal age, fetal nuchal translucency thickness and serum free β-hCG, as in singleton pregnancy, without the use of serum PAPP-A. Alternatively, PAPP-A can be included but only after appropriate adjustment for the interval between estimated gestational age at fetal demise and blood sampling. Copyright © 2019 ISUOG. Published by John Wiley & Sons Ltd.

Keyphrases

gestational age
birth weight
preterm birth
pregnancy outcomes
optical coherence tomography
randomized controlled trial
meta analyses
weight loss