Aspirin desensitization in NSAID-exacerbated respiratory disease and its outcomes in the clinical course of asthma: A systematic review of the literature and meta-analysis.
Isabel ErasoSaveria SangiovanniEliana I MoralesLiliana F TrujilloPublished in: PloS one (2021)
Due to the small number of studies included in this systematic review, conclusions should be made with caution. AD shows a trend towards improving lung function (FEV1) following 6 months of treatment, although no conclusions can be made regarding the use of corticosteroids or the frequency of acute exacerbations. AD appears to reduce both symptom and medication scores. Additional RCTs are needed to fully assess the efficacy of AD in reducing bronchial symptoms in patients with NERD.
Keyphrases
- lung function
- chronic obstructive pulmonary disease
- cystic fibrosis
- systematic review
- air pollution
- liver failure
- low dose
- meta analyses
- healthcare
- respiratory failure
- cardiovascular events
- type diabetes
- randomized controlled trial
- metabolic syndrome
- emergency department
- case control
- insulin resistance
- sleep quality
- depressive symptoms
- combination therapy
- acute respiratory distress syndrome
- electronic health record