TSPAN1 overexpression as an indicator of poor prognosis in estrogen receptor-positive breast cancer.

Xiangjuan LiuJiahong ZhangJun ZhaoYan ChengDandan Jiang

Published in: Translational cancer research (2024)

TSPAN1 modulates downstream extracellular matrix (ECM) receptor signaling cascades and promotes cellular proliferation and invasion in breast cancer. TSPAN1 inhibition may be a potential new treatment strategy for breast cancer.

Keyphrases

extracellular matrix
poor prognosis
estrogen receptor
positive breast cancer
long non coding rna
cell proliferation
transcription factor
risk assessment
combination therapy
climate change
human health
childhood cancer