Cardiovascular outcomes in obstructive sleep apnoea and implications of clinical phenotyping on effect of CPAP treatment.

Pei-Hang XuDaniel Y T FongMacy M S LuiDavid C L LamMary Sau-Man Ip

Published in: Thorax (2022)

OSA-related TST90 and mean heart rate, but not AHI, were robust predictors of MACEs. A clinical phenotype subgroup who demonstrated beneficial effect of CPAP treatment was identified.

Keyphrases

heart rate
obstructive sleep apnea
positive airway pressure
heart rate variability
blood pressure
randomized controlled trial
sleep apnea
depressive symptoms
study protocol
single cell
drug induced