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Cardiovascular outcomes in obstructive sleep apnoea and implications of clinical phenotyping on effect of CPAP treatment.

Pei-Hang XuDaniel Y T FongMacy M S LuiDavid C L LamMary Sau-Man Ip
Published in: Thorax (2022)
OSA-related TST90 and mean heart rate, but not AHI, were robust predictors of MACEs. A clinical phenotype subgroup who demonstrated beneficial effect of CPAP treatment was identified.
Keyphrases
  • heart rate
  • obstructive sleep apnea
  • positive airway pressure
  • heart rate variability
  • blood pressure
  • randomized controlled trial
  • sleep apnea
  • depressive symptoms
  • study protocol
  • single cell
  • drug induced