Feasibility and Acceptability of Metformin to Augment Low Milk Supply: A Pilot Randomized Controlled Trial.
Laurie A Nommsen-RiversAmy ThompsonSarah RiddleLaura WardErin WagnerEileen KingPublished in: Journal of human lactation : official journal of International Lactation Consultant Association (2019)
Although results trend toward hypothesized direction, trial feasibility concerns include late enrollment and only 20% of metformin-assigned participants sustaining improved milk output to Day 28, with none perceiving metformin worthwhile. Better tools are needed to identify and treat metabolically-driven low milk production. Registered at ClinicalTrials.gov (NCT02179788) on 02/JUL/2014.