Acetylshikonin promoting PI3K/Akt pathway and inhibiting SOX4 expression to delay intervertebral disc degeneration and low back pain.
Yuming HuangLinchuan LeiZhuoyang ZhaoZemin LiHua WangShunlun ChenJinjian ZhengGuowei JiangXingyu GuoJiamin LiJianru WangZhaomin ZhengFan ChenPublished in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society (2023)
Acetylshikonin delays IVDD-induced LBP by inhibiting SOX4 expression through the PI3K/Akt pathway. These findings offer potential therapeutic targets for future treatments. This article is protected by copyright. All rights reserved.