Association of the PAX6 gene with extreme myopia rather than lower grade myopias.

Shu Min TangLi MaShi Yao LuYu Meng WangKa Wai KamPancy O S TamAlvin L YoungChi Pui PangJason C S YamLi Jia Chen

Published in: The British journal of ophthalmology (2018)

This study provides additional evidence suggesting that the PAX6 SNP rs644242 is associated with extreme myopia but not lower grade myopia. Thus, PAX6 may be implicated in the development or progression into severe myopia. Further longitudinal studies are warranted.

Keyphrases

optic nerve
genome wide
climate change
copy number
early onset
cross sectional
transcription factor
genetic diversity
genome wide analysis