Clinical outcomes in children living with HIV treated for non-severe tuberculosis in the SHINE Trial.
Chishala ChabalaEric WobudeyaMarieke M van der ZalmMonica KapasaPriyanka RaichurRobert MboiziMegan PalmerAarti Avinash KinikarSyed HissarVeronica MulengaVidya MavePhilippa MusokeAnneke C HesselingHelen M McIlleronDiana M GibbAngela CrookAnna Turkovanull nullPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)
We found no evidence of a difference in TB outcomes between 4 and 6 months of treatment for CLWH treated for non-severe TB. Irrespective of TB treatment duration, CLWH had higher rates of mortality and hospitalization than HIV-uninfected counterparts.
Keyphrases
- mycobacterium tuberculosis
- hiv infected
- antiretroviral therapy
- hiv aids
- hepatitis c virus
- clinical trial
- early onset
- young adults
- human immunodeficiency virus
- hiv positive
- cardiovascular events
- metabolic syndrome
- adipose tissue
- randomized controlled trial
- combination therapy
- pulmonary tuberculosis
- hiv testing
- drug induced
- replacement therapy
- open label
- electronic health record
- smoking cessation