Patterns of B-cell lymphocyte expression changes in pre- and post-malignant prostate tissue are associated with prostate cancer progression.

Sudha M SadasivanIan M LovelessYalei ChenNilesh S GuptaRyan SaniiKevin R BobbittDhananjay A ChitaleSean R WilliamsonAndrew G RundleBenjamin A Rybicki

Published in: Cancer medicine (2024)

Longitudinal and spatial expression patterns of both CD3+ and CD20+ suggest that increased expression in benign glands during prostate carcinogenesis is associated with an aggressive disease course.

Keyphrases

prostate cancer
poor prognosis
radical prostatectomy
benign prostatic hyperplasia
nk cells
peripheral blood