Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis.
Shintaro AkiyamaJacob E OllechCindy TraboulsiVictoria RaiLaura R GlickYangtian YiJoseph RundeAndrea D OlivasChristopher R WeberRussell D CohenKinga B Skowron OlorteguiRoger D HurstKonstantin UmanskiyBenjamin D ShoganMichele A RubinSushila R DalalAtsushi SakurabaJoel PekowEugene B ChangJohn HartNeil H HymanDavid T RubinPublished in: Digestive diseases and sciences (2022)
We identify histologic features of colectomy specimens in UC that predict subsequent pouch phenotypes. Particularly, deep inflammation in the resected colon was significantly associated with pouch fistulas, a pouch phenotype with poor prognosis.