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Intravenous isavuconazole can be administered 5 days-a-week. A possibility suggested by a real-life observation.

Elio CastagnolaAlessio MesiniCarolina SaffiotiSebastiano BarcoRoberto BandettiniSandro DallorsoGiuliana CarregaMaurizio MianoElena PalmisaniCarlo Dufour
Published in: Journal of chemotherapy (Florence, Italy) (2020)
In this report it is shown that intravenous formulation of isavuconazole could be administered 5/7 days a week in patients who can not swallow capsules, once the steady state has been stably reached and maintained, thanks to its very long half-life. In this case TDM should be highly recommended.
Keyphrases
  • high dose
  • drug delivery
  • placebo controlled
  • randomized controlled trial
  • low dose