Genetic evidence for imported malaria and local transmission in Richard Toll, Senegal.

Rachel F DanielsStephen F SchaffnerYakou DieyeGnagna DiengMichael HainsworthFatou B FallCoumba Ndoffene DioufMedoune NdiopMoustapha CisseAlioune Badara GueyeOumar SarrPhilippe GuinotAwa B DemeAmy K BeiMouhamad SyJulie ThwingBronwyn MacInnisDuncan EarleCaterina GuinovartDoudou SeneDaniel L HartlDaouda NdiayeRichard W SteketeeDyann F WirthSarah K Volkman

Published in: Malaria journal (2020)

These data indicate that, while a large number of infections may have been imported, there remains ongoing local malaria transmission in Richard Toll. These proof-of-concept findings underscore the value of genetic data to identify parasite relatedness and patterns of transmission to inform optimal intervention selection and placement.

Keyphrases

plasmodium falciparum
electronic health record
genome wide
randomized controlled trial
big data
copy number
dna methylation
machine learning
deep learning