No efficacy of transcranial direct current stimulation on chronic migraine with medication overuse: A double blind, randomised clinical trial.
Licia GrazziSusanna UsaiNadia BologniniEleonora GrignaniEmanuela SansoneIrene TramacereAngelo MaravitaGiuseppe Lauria PinterPublished in: Cephalalgia : an international journal of headache (2020)
Transcranial direct current stimulation did not influence the short and long-term course of chronic migraine with medication overuse after acute drug withdrawal. Behavioral and educational measures and support for patients' pain management could provide long-term improvement and low relapse rate.Trial registration number NCT04228809.
Keyphrases
- transcranial direct current stimulation
- clinical trial
- pain management
- working memory
- study protocol
- open label
- end stage renal disease
- phase ii
- adverse drug
- healthcare
- phase iii
- ejection fraction
- newly diagnosed
- chronic pain
- double blind
- randomized controlled trial
- prognostic factors
- emergency department
- drug induced
- patient reported outcomes
- patient reported
- placebo controlled