Within-person fluctuations over three years in depression, anxiety, fatigue, and health-related quality of life in multiple sclerosis.

Ruth Ann MarrieCharles N BernsteinCasandra DolovichJames M BoltonLesley A GraffCarol A HitchonLisa M LixJames J MarriottJohn D Fisk

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2023)

Within-person increases in symptoms of depression, anxiety and fatigue, and comorbidity count are associated with HRQoL decreases among adults with MS, highlighting the potential magnitude of individual benefit of intervention for these symptoms.

Keyphrases

sleep quality
multiple sclerosis
depressive symptoms
physical activity
randomized controlled trial
mass spectrometry
white matter
human health