Atrial Fibrillation can adversely impact Heart Failure with Preserved Ejection Fraction by its association with Heart Failure Progression and Mortality: A Post-Hoc Propensity Score-Matched Analysis of the TOPCAT Americas Trial.

Sanjeev Saksena April E Hebert Sanghamitra MohantyDhanunjaya R LakkireddyDipen C Shah Luigi Di Biase Thorsten Lewalter Rangadham Nagarakanti Pasquale Santangeli

Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)

TOPCAT trial is registered at www.clinicaltrials.gov:identifier NCT00094302.

Keyphrases

heart failure
atrial fibrillation
phase iii
study protocol
phase ii
clinical trial
randomized controlled trial
open label
risk factors
type diabetes
left atrial
cardiac resynchronization therapy
acute heart failure
percutaneous coronary intervention
cardiovascular disease
left atrial appendage
placebo controlled