Thrombolytics in Cardiac Arrest from Pulmonary Embolism: A Systematic Review and Meta Analysis.

Jordan Robert FeltesMargarita PopovaYasir HusseinAyal PierceDavid Yamane

Published in: Journal of intensive care medicine (2023)

Use of intravenous thrombolytics in cardiac arrest due to confirmed or presumed PE is associated with increased ROSC but not survival to hospital discharge or change in bleeding complications. Larger randomized studies are needed. Currently, we recommend continuing to follow existing consensus guidelines which support use of thrombolytics for this indication.

Keyphrases

cardiac arrest
pulmonary embolism
cardiopulmonary resuscitation
inferior vena cava
clinical practice
double blind
open label
high dose
placebo controlled
phase iii
atrial fibrillation
phase ii
clinical trial
randomized controlled trial
study protocol