Cell autonomous expression of CXCL-10 in JAK2V617F-mutated MPN.

Tina M SchnöderJudith EberhardtMichael KoehlerHolger B BierhoffSönke WeinertAkhilesh Datt PandeySubbaiah Chary NimmagaddaDenise WolleschakKorinna JöhrensFlorian H Heidel

Published in: Journal of cancer research and clinical oncology (2017)

Our data provide first evidence for a link between oncogenic JAK2V617F signaling and cell intrinsic induction of CXCL10 induced by activated NFkB signaling.

Keyphrases

single cell
cell therapy
poor prognosis
stem cells
big data
machine learning
bone marrow
artificial intelligence