Comparison between low disease activity or DAS remission as treatment target in patients with early active rheumatoid arthritis.
Gülşah AkdemirIris M MarkusseSytske Anne BergstraRobbert J GoekoopEsmeralda T MolenaarJohannes H L M van GroenendaelPit J S M KerstensWillem F LemsTom W J HuizingaCornelia F AllaartPublished in: RMD open (2018)
In patients with early active RA who start with comparable disease-modifying antirheumatic drug+prednisone combination therapy, subsequent DAS <1.6 steered treatment is associated with similar clinical and radiological outcomes over time as DAS ≤2.4 steered treatment; however, in the DAS <1.6 steered group, more patients achieved remission and drug-free remission.
Keyphrases
- disease activity
- rheumatoid arthritis
- rheumatoid arthritis patients
- systemic lupus erythematosus
- combination therapy
- ankylosing spondylitis
- juvenile idiopathic arthritis
- molecular dynamics
- interstitial lung disease
- molecular dynamics simulations
- ejection fraction
- newly diagnosed
- chronic kidney disease
- drug induced
- systemic sclerosis
- adipose tissue
- skeletal muscle
- ulcerative colitis
- replacement therapy
- adverse drug