Gut microbiota-derived short-chain fatty acids regulate group 3 innate lymphoid cells in HCC.

Chupeng HuBingqing XuXiaodong WangWen-Hua WanJinying LuDeyuan KongYu JinWenhua YouHua SunXiaoxin MuDongju FengYun Chen

Published in: Hepatology (Baltimore, Md.) (2022)

These findings suggested that modifying bacteria, changing SCFAs, reducing IL-17A-producing ILC3 infiltration, and combining with immune checkpoint inhibitors will contribute to the clinical treatment of HCC.

Keyphrases

fatty acid
induced apoptosis
cell cycle arrest
cell death
oxidative stress
endoplasmic reticulum stress
replacement therapy