Effects of artemisinin and cisplatin on the malignant progression of oral leukoplakia. In vitro and in vivo study.
Mateus José DutraIsabella Souza MaltaMaria Letícia de Almeida LançaLuana Marotta Reis de VasconcellosDaniela AdornoJosé Antonio JaraEstela KaminagakuraPublished in: Journal of cancer research and clinical oncology (2024)
Expression of proteins related to ICD and apoptosis did not increase with treatments, and CSP was shown to reduce immunogenic pathways in SCC-180, while reducing cell migration. ART did not prevent the malignant progression of OL in vivo; CSP did despite significant adverse effects.