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Location and condition based reconstruction of colon cancer microbiome from human RNA sequencing data.

Gaia SambruniAngeli D MacandogJakob WirbelDanilo CagninaCarlotta CatozziTiziano DallavillaFrancesca BorgoNicola FazioUberto Fumagalli-RomarioWanda L PetzTeresa ManzoSimona P RavendaGeorg ZellerLuigi NeziMartin H Schaefer
Published in: Genome medicine (2023)
We implemented an approach to concurrently analyse clinical and molecular properties of the tumour as well as the composition of the associated microbiome. Our results may improve patient stratification and pave the path for mechanistic studies on microbiota-tumour crosstalk.
Keyphrases
  • endothelial cells
  • single cell
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  • induced pluripotent stem cells
  • electronic health record
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  • case control
  • single molecule