A probiotic intervention on pain hypersensitivity and microbiota composition in patients with osteoarthritis pain: Study protocol for a randomized controlled trial.

Jorge Hugo VillafañeMarco SavoldiPedro BerjanoJorge Hugo Villafañe

Published in: Archives of rheumatology (2021)

A reduction in pain hypersensitivity in patients with knee OA-related pain could suggest an involvement of microbiota, or part of it, in chronic pain state mechanisms.

Keyphrases

chronic pain
pain management
neuropathic pain
knee osteoarthritis
randomized controlled trial
total knee arthroplasty
rheumatoid arthritis
drug induced