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Sex differences in brain atrophy in dementia with Lewy bodies.

Javier OltraAnnegret HabichChristopher G SchwarzZuzana NedelskaScott A PrzybelskiAnna InguanzoPatricia Diaz-GalvanVal J LoweKetil OppedalFrederic BlancAfina W LemstraJakub HortAlessandro PadovaniIrena RektorováLaura BonanniFederico MassaMilica G KrambergerJohn Paul TaylorJón G SnædalZuzana WalkerAngelo AntoniniBàrbara SeguraCarme JunqueErik WestmanBradley F BoeveDag AarslandKejal KantarciDaniel Ferreira
Published in: Research square (2023)
This study demonstrates sex differences on brain atrophy in probable DLB. While male DLB patients have a more widespread pattern of cortical atrophy at younger ages, these sex differences tend to disappear with increasing age. Longitudinal studies will help establish these cross-sectional findings and inform on sex and age considerations to the use of MRI in clinical routine, as the field moves towards precision medicine.
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