Monitoring response to a clinically relevant IDH inhibitor in glioma-Hyperpolarized 13 C magnetic resonance spectroscopy approaches.

Donghyun HongYaewon KimChandrasekhar MushtiNoriaki MinamiJing WuMurali Krishna CherukuriRolf E SwensonDaniel B VigneronSabrina M Ronen

Published in: Neuro-oncology advances (2023)

Our findings point to the clinical potential of HP αKG, which recently received FDA investigational new drug approval for research, for noninvasive localized imaging of IDHmut status.

Keyphrases

high resolution
low grade
randomized controlled trial
human health
emergency department
risk assessment
adverse drug
photodynamic therapy
mass spectrometry
study protocol
high grade
open label
phase iii