Behavioural effects of methylphenidate in the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis protocol.

Douglas Teixeira Leffa Alana Castro Panzenhagen Diego Luiz Rovaris Claiton Henrique Dotto Bau Luis Augusto Rohde Eugênio Horácio GrevetGabriel Natan Pires

Published in: BMJ open science (2018)

Data extraction will be performed by two independent authors according to a standardised form. Studies will be grouped according to the behavioural outcomes reported, and a meta-analysis will be performed for each group. The influence of predefined covariates on the effects of MPH will be evaluated using meta-regression and sensitivity analyses. Data will be reported following PRISMA guidelines.

Keyphrases

attention deficit hyperactivity disorder
autism spectrum disorder
electronic health record
big data
working memory
blood pressure
randomized controlled trial
machine learning
type diabetes
clinical practice
data analysis
metabolic syndrome
skeletal muscle
weight loss
glycemic control