Cerebrospinal Fluid Cytokine and Chemokine Profiles in Central Nervous System Sarcoidosis: Diagnostic and Immunopathologic Insights.
Georgios MangiorisSean J PittockBinxia YangJames P FryerWilliam S HarmsenDivyanshu DubeyEoin Patrick FlanaganAlfonso Sebastian Lopez-ChiribogaAndrew McKeonJohn R MillsIvana VodopivecWilliam Oliver TobinMichel ToledanoAllen J AksamitAnastasia ZekeridouPublished in: Annals of neurology (2024)
NS CSF cytokine/chemokine profiles suggest T cell (mainly T helper cell type 1), macrophage, and B-cell involvement. These signatures aid in NS diagnosis, indicate disease activity, and suggest therapeutic avenues. ANN NEUROL 2024.