Successful treatment of severe interstitial pneumonia by removal of circulating autoantibodies: a case series.
Philipp EllerHolger FlickGernot SchilcherFlorentine Moazedi-FürstKathrin EllerEmina TalakicJosef HermannYannick AllanoreHorst OlschewskiPublished in: BMC pulmonary medicine (2021)
Patients suffering from severe connective tissue disease-associated interstitial lung disease and respiratory failure may benefit from an aggressive immunosuppressive regimen and extracorporeal blood purification with rapid reduction of circulating autoantibodies. The impressive clinical responses in this small case series warrant a controlled clinical trial.
Keyphrases
- respiratory failure
- interstitial lung disease
- clinical trial
- systemic sclerosis
- end stage renal disease
- systemic lupus erythematosus
- extracorporeal membrane oxygenation
- ejection fraction
- chronic kidney disease
- rheumatoid arthritis
- mechanical ventilation
- idiopathic pulmonary fibrosis
- prognostic factors
- peritoneal dialysis
- randomized controlled trial
- drug induced
- double blind
- phase iii