Health-related quality of life, neuropsychiatric symptoms and structural brain changes in clinically isolated syndrome.

Eva HyncicovaAdam KalinaMartin VyhnalekTomas NikolaiLukas MartinkovicJiri LisyJakub HortEva MeluzinovaJan Laczó

Published in: PloS one (2018)

Mild depressive symptoms and anxiety with decreased HRQoL are present in patients with CIS. Neuropsychiatric symptoms contributing to decreased HRQoL are the result of structural brain changes and require complex therapeutic approach in patients with CIS.

Keyphrases

sleep quality
depressive symptoms
white matter
resting state
cerebral ischemia
social support
multiple sclerosis
case report