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Stromal cell-derived factor-1/Exendin-4 cotherapy facilitates the proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells in vitro and promotes periodontal bone regeneration in vivo.

Qianyu LiangLingqian DuRui ZhangWenyan KangShaohua Ge
Published in: Cell proliferation (2021)
SDF-1/EX-4 cotherapy synergistically regulated PDLSC activities, promoted periodontal bone formation, thereby providing a new strategy for periodontal bone regeneration.
Keyphrases
  • bone regeneration
  • stem cells
  • endothelial cells
  • bone marrow
  • signaling pathway
  • transcription factor
  • induced pluripotent stem cells
  • pluripotent stem cells
  • mesenchymal stem cells