The Relation Between Adult Weight Gain, Adipocyte Volume, and the Metabolic Profile at Middle Age.
Inge VerkouterRaymond NoordamNellie Y LohKo Willems van DijkPeter L ZockDennis O Mook-KanamoriSaskia Le CessieFrits R RosendaalFredrik KarpeCostantinos ChristodoulidesRenée de MutsertPublished in: The Journal of clinical endocrinology and metabolism (2021)
Adult weight gain is associated with specific metabolomic alterations of which the higher lipoprotein concentrations were likely contributed by larger adipocyte volumes, presumably linking weight gain to cardiometabolic disease.