Knocking-down long non-coding RNA LINC01094 prohibits chondrocyte apoptosis via regulating microRNA-577/metal-regulatory transcription factor 1 axis.

Feiri HuangZhongliang SuJie YangXizhen ZhaoYaozeng Xu

Published in: Journal of orthopaedic surgery (Hong Kong) (2024)

Silencing of LINC01094 represses the apoptosis of chondrocytes through upregulating miR-577 expression and downregulating MTF1 levels, providing a preliminary insight for the treatment of OA in the future.

Keyphrases

long non coding rna
poor prognosis
transcription factor
endoplasmic reticulum stress
cell cycle arrest
oxidative stress
cell death
current status
knee osteoarthritis
long noncoding rna
smoking cessation