A double-blind, placebo-controlled, randomised trial to assess the effect of liraglutide on ectopic fat accumulation in South Asian type 2 diabetes patients.
Huub J van EykElisabeth H M PaimanMaurice B BizinoPaul de HeerPetronella H Geelhoed-DuijvestijnAan V KharagjitsinghJohannes W A SmitHildo J LambPatrick C N RensenIngrid M JazetPublished in: Cardiovascular diabetology (2019)
While the intention-to-treat analysis did not show effects of liraglutide on ectopic fat and HbA1c, per-protocol analysis showed that liraglutide decreases visceral adipose tissue volume, which was associated with improved glycaemic control in South Asians. Trial registration NCT02660047 (clinicaltrials.gov). Registered 21 January 2016.