HMG-CoA reductase inhibitors (statins) and acute kidney injury: A secondary analysis of renal study outcomes.

In the RENAL study cohort, baseline statin use was not associated with mortality. Our findings do not support a protective role of statins in ICU patients with severe AKI. Clinical Trials registration number for the RENAL study: NCT00221013, the date of registration: September 14, 2005.