Prenatal Household Air Pollution Alters Cord Blood Mononuclear Cell Mitochondrial DNA Copy Number: Sex-Specific Associations.

Seyram KaaliDarby JackRupert DeliminiLisa HuKatrin BurkartJones Opoku-MensahAshlinn QuinnKenneth Ayuurebobi Ae-NgibiseBlair WylieEllen Abrafi Boamah-KaaliSteven ChillrudSeth Owusu-AgyeiPatrick L KinneyAndrea A BaccarelliKwaku Poku AsanteAlison Lee

Published in: International journal of environmental research and public health (2018)

Increased prenatal HAP exposure reduces CBMC mtDNAcn, suggesting cumulative prenatal oxidative stress injury. An LPG stove intervention may reverse this effect. Boys appear most susceptible.

Keyphrases

mitochondrial dna
copy number
cord blood
pregnant women
oxidative stress
air pollution
genome wide
randomized controlled trial
dna methylation
cell therapy
particulate matter
gene expression
lung function
bone marrow
chronic obstructive pulmonary disease
heat stress