Treatment of congenital adrenal hyperplasia in children aged 0-3 years: a retrospective multicenter analysis of salt supplementation, glucocorticoid and mineralocorticoid medication, growth and blood pressure.
Uta NeumannAnnelieke van der LindeRuth E KroneNils P KroneAyla GüvenTülay GüranHeba ElsedfySukran PoyrazogluFeyza DarendelilerTania A S S BachegaAntonio BalsamoSabine Elisabeth HannemaNiels BirkebaekAna VieitesAjay ThankamonyMartine CoolsTatjana MilenkovicWalter BonfigEduardo Correa CostaNavoda AtapattuLiat de VriesGuilherme Guaragna-FilhoMarta KorbonitsKlaus MohnikeJillian BryceSyed Faisal AhmedBernard VoetOliver BlankensteinHedi L Claahsen-van der GrintenPublished in: European journal of endocrinology (2022)
In children treated with additional salt supplementation, FC and HC dosages are lower during the first months of life but without differences in weight, length and BP until 3 years of age compared to NST children. All children showed an increase in BMI-SDS and a high rate of BP readings >P95 until 3 years, indicating the start of weight gain and negative effects on blood pressure already in very early life.