Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF- β /Smad Pathway.

Yu Wang Sibo Sun Kai Wang Mingjiong Zhang Min Li Yumin Zan Qiqing Huang Shuangshuang Wu Weihong Zhao Wei Xu Jianqing Wu

Published in: Mediators of inflammation (2022)

Our results imply the profibrotic role for IL-19 through direct effects on lung fibroblasts and the potential of targeting IL-19 for therapeutic intervention in pulmonary fibrosis.

Keyphrases

pulmonary fibrosis
transforming growth factor
randomized controlled trial
epithelial mesenchymal transition
risk assessment
drug delivery