microRNA-193a-5p inhibits migration of human HT-29 colon cancer cells via suppression of metastasis pathway.

Naghmeh ShirafkanNavid ShomaliTohid KazemiDariush ShanehbandiMehri GhasabiElham BaghbaniMaziar GanjiVahid KhazeBehzad Mansoori Behzad Baradaran

Published in: Journal of cellular biochemistry (2018)

Our results indicated that miR-193a-5p acts as a tumor suppressor miRNA and its downregulation plays an important role in metastasis via upregulation of metastasis-related genes in CRC. Therefore, it can be considered as a potential therapeutic target for applying in CRC management in the future.

Keyphrases

cell proliferation
endothelial cells
signaling pathway
poor prognosis
induced pluripotent stem cells
climate change
long non coding rna