Effects of l-arginine supplementation in patients with sickle cell disease: A systematic review and meta-analysis of clinical trials.
Alireza SadeghiEhsan TaherifardNiloofar Dehdari EbrahimiElham RafieiFarshad HadianfardErfan TaherifardPublished in: Health science reports (2023)
Our meta-analysis showed that l-arginine use for SCD could be beneficial, increase hemoglobin F and exert blood pressure-lowering and hepatoprotective properties. However, for a firm conclusion and widespread use of l-arginine for these patients, more studies are needed.
Keyphrases
- sickle cell disease
- nitric oxide
- blood pressure
- clinical trial
- systematic review
- end stage renal disease
- ejection fraction
- case control
- chronic kidney disease
- amino acid
- peritoneal dialysis
- type diabetes
- prognostic factors
- randomized controlled trial
- heart rate
- adipose tissue
- patient reported
- phase iii
- insulin resistance