Contrasted central effects of n-3 versus n-6 diets on brain functions in diet-induced obesity in minipigs.
Charles-Henri MalbertDavid Val-LailletPaul MeuriceJean-Paul LallèsJacques DelaruePublished in: Nutritional neuroscience (2021)
: The minute changes in brain metabolism in obese pigs feed with fish oil compared with saturated fatty acids were sufficient to induce detrimental changes in heart rate variability. On the contrary, the BBB's decreased permeability in n-3 and n-6 PUFAs groups was protective against an obesity-driven damaged BBB.
Keyphrases
- weight loss
- heart rate variability
- metabolic syndrome
- fatty acid
- insulin resistance
- blood brain barrier
- heart rate
- bariatric surgery
- type diabetes
- resting state
- white matter
- high fat diet induced
- weight gain
- cerebral ischemia
- adipose tissue
- functional connectivity
- endothelial cells
- blood pressure
- subarachnoid hemorrhage