Growth differentiation factor-15 is associated with age-related monocyte dysfunction.

Brandt D PenceJohnathan R YarbroRussell S Emmons

Published in: Aging medicine (Milton (N.S.W)) (2020)

These results suggest that GDF-15 is a potential circulating factor affecting a variety of monocyte functions and promoting monocyte immunosenescence and thus may be an attractive candidate for therapeutic intervention to ameliorate this.

Keyphrases

dendritic cells
endothelial cells
peripheral blood
randomized controlled trial
oxidative stress
immune response
climate change