Tuberculosis at the animal-human interface in the Ugandan cattle corridor using a third-generation sequencing platform: a cross-sectional analysis study.
Matthew Flinn PullenDavid R BoulwareSrinand SreevatsanJoel BaziraPublished in: BMJ open (2019)
Ethical approval was obtained from both the University of Minnesota IRB committee and the Ugandan National Council for Science and Technology-Research Ethics Committee. Samples were obtained after patients signed an informed consent indicating samples could be retained and used for research purposes. All samples are deidentified, with only basic demographic and geographic information being retained per national tuberculosis (TB) recording guidelines. Significant drug resistance results will be referred back to the local TB control officer to inform patient care. Final results of the study will be submitted to infectious disease-specific journals and will be submitted to the annual Infectious Diseases Society of America (IDSA) meeting.
Keyphrases
- infectious diseases
- mycobacterium tuberculosis
- public health
- end stage renal disease
- newly diagnosed
- quality improvement
- ejection fraction
- systematic review
- pulmonary tuberculosis
- hiv aids
- randomized controlled trial
- high throughput
- healthcare
- emergency department
- peritoneal dialysis
- machine learning
- human immunodeficiency virus
- decision making
- deep learning
- adverse drug