Effectiveness of preconception weight loss interventions on fertility in women: a systematic review and meta-analysis.
Ann E CaldwellAnna M GorczycaAndrew P BradfordJacinda M NicklasRobert N MontgomeryHeather SmythShannon PretzelThy NguyenKristen DeSantoCelia ErnstromNanette SantoroPublished in: Fertility and sterility (2024)
Pregnancy rates were higher in women undergoing preconception weight loss interventions with no impact on live birth or miscarriage rates. Findings do not support one-size-fits-all recommendation for weight loss through lifestyle modification and/or medication in women with overweight or obesity immediately before conception to improve live birth or miscarriage outcomes.
Keyphrases
- weight loss
- pregnancy outcomes
- bariatric surgery
- roux en y gastric bypass
- polycystic ovary syndrome
- gastric bypass
- physical activity
- glycemic control
- pregnant women
- randomized controlled trial
- weight gain
- gestational age
- systematic review
- healthcare
- insulin resistance
- metabolic syndrome
- breast cancer risk
- type diabetes
- cardiovascular disease
- skeletal muscle