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Effects of PPAR-γ agonists on oral cancer cell lines: Potential horizons for chemopreventives and adjunctive therapies.

Jeffrey A HallMark RustenRaed D AbughazalehBeverly R WuertzVannesa SouksavongPaul J EscherFrank G Ondrey
Published in: Head & neck (2020)
Our results suggest these agents, in addition to activating PPAR-γ, can downregulate NF-κB and potentiate apoptosis in oral cancer cells.
Keyphrases
  • signaling pathway
  • oxidative stress
  • insulin resistance
  • cell cycle arrest
  • pi k akt
  • endoplasmic reticulum stress
  • fatty acid
  • cell death
  • lps induced
  • nuclear factor
  • human health
  • type diabetes
  • cell proliferation