Bile multi-omics analysis classifies lipid species and microbial peptides predictive of carcinoma of gallbladder.

Nupur SharmaManisha YadavGaurav TripathiBabu MathewVasundhra BindalSanyam FalariViniyendra PamechaJaswinder Singh Maras

Published in: Hepatology (Baltimore, Md.) (2022)

Bile samples of patients with CAGB showed significant reduction in lipid species and increase in bacterial taxa. Our study identifies a core set of bile lipidome and metaproteome signatures which may offer universal utility for early diagnosis of CAGB.

Keyphrases

genome wide
fatty acid
microbial community
single cell
dna methylation
gene expression