miR-6718-5p and miR-4329 can be used as potential biomarkers for acute myocardial infarction.

Shaoyuan Chen Hongcheng Fang Rongzhi Liu Yeqing Fang Zhenyuan Wu Peiyi Xie

Published in: Journal of cardiac surgery (2021)

Compared with healthy individuals, 544 miRNAs were upregulated and 518 miRNAs were downregulated in AMI patients preoperatively. Among these miRNAs, we selected miR-6718 and miR-4329 for qPCR verification. The expression of miR6718 and miR-4329 in patients with myocardial infarction was significantly lower than that in normal controls.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
acute myocardial infarction
poor prognosis
left ventricular
heart failure
ejection fraction
newly diagnosed
prognostic factors
chronic kidney disease
patient reported outcomes
binding protein