A Systematic Review of MRI Studies and the "Emotional paiN and social Disconnect (END)" Brain Model of Suicidal Behavior in Youth.

Olga TymofiyevaKatherine W ReevesChace ShawEric LopezSepehr AzizJeffrey E MaxTony T Yang

Published in: Behavioural neurology (2023)

Our proposed END brain model of suicidal behavior in youth, if confirmed by future prospective studies, can have implications for clinical goals of early detection, risk stratification, and intervention development. Treatments that target emotional pain and social disconnect may be ideal interventions for reducing suicidality in adolescents.

Keyphrases

physical activity
mental health
young adults
chronic pain
depressive symptoms
pain management
resting state
healthcare
white matter
neuropathic pain
randomized controlled trial
case control
magnetic resonance imaging
functional connectivity
multiple sclerosis
brain injury