Incidence of venous thromboembolism and bleeding in patients with malignant central nervous system neoplasm: Systematic review and meta-analysis.
Viviane Cordeiro VeigaStela Verzinhasse PeresThatiane L V D P OstolinFlavia Regina MoraesTalita Rantin BelucciCarlos Afonso ClaraAlexandre Biasi CavalcantiFeres Eduardo Aparecido Chaddad-NetoGabriel Novaes de Rezende BatistellaIuri Santana NevilleAlex M BaetaCamilla Akemi Felizardo Yamadanull nullPublished in: PloS one (2024)
Our study showed variability in the pooled incidence for both overall events and subgroup analyses. It was highlighted that individuals over 60 years old or diagnosed with GBM had a higher pooled incidence of VTE among those with overall CNS malignancies. It is important to note that the results of this meta-analysis refer mainly to studies carried out in high-income countries. This highlights the need for additional research in Latin America, and low- and middle-income countries.